Thesis On Staphylococcus Aureus

Thesis On Staphylococcus Aureus-58
aureus but only living in urban of children significantly associated with MRSA. So, decolonization of nasal carriers of MRSA and reducing the number of students per classroom should be addressed.Moreover, regular large scale survey should be conducted to assess the burden and intervene accordingly. aureus) is a Gram-positive, catalase-positive, and coagulase-positive bacteria commonly found mainly on the skin and nasal mucosa of most healthy individuals [1].

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aureus to grow in the presence of methicillin and other β-lactam antibiotics [12, 13].

PBP2a is located in the bacterial cell wall and has a low binding affinity for β-lactam antibiotics [14].

Also to indicate the prevention and control measures in the general community, it will also be used as preliminary information for future studies.

The study was conducted in five governmental urban elementary schools in Gondar town and five governmental rural elementary schools surrounding Gondar town; Gondar town is the capital of North Gondar administrative zone, in Amhara region, Northwest Ethiopia.

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We use cookies to offer you a better experience, personalize content, tailor advertising, provide social media features, and better understand the use of our services.Staphylococcus aureus exhibits increasing virulence and resistance to various antibiotics, complicating prevention, and treatment of infections [6].Virulence factors are tightly regulated and act to degrade host cells, tissues, change the immune response, and enable for the dissemination inside and outside the host cell [7].Odds ratio and logistic regression were used for statistical association. The carriage rate in urban schools was 83/622 (13.3%) whereas it was 60/622 (9.6%) in rural schools.P-value ≤ 0.05 at 95% CI was considered for statistical association. Of the 622 school children, the overall prevalence of S. The prevalence of MRSA among urban schools, 9.1%, was higher than their urban counterparts, 0.7%.A community-based comparative cross-sectional study was conducted to determine nasal carriage rate, antimicrobial susceptibility pattern, and associated factors of Staphylococcus aureus with special emphasis on MRSA among elementary school children from January 2018.School children from recruited schools who gave sociodemographic information and nasal swab samples were included whereas children who were unable to give sociodemographic information, nasal swab specimen, and those who were on antibiotic therapy at the time of data collection were excluded All randomly selected school children from recruited schools who have agreed to give sociodemographic information and nasal swab samples were included.Children who were unable to give sociodemographic information and nasal swab specimen and those who were involuntary to participate in the study due to different reasons and children who were on antibiotic therapy at the time of data collection were also excluded.Single population proportion formula was used to determine the sample size and the calculated sample size was 258.However, adding 20% nonresponse rate and a design effect of two, the final calculated sample size was 622.A multistage sampling technique was used to select schools by using simple random sampling technique and stratifying the schools to grades and sections.


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